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The antibody against DIO2 was raised in rabbit using the Synthetic peptide of Human DIO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against DIO2 was raised in rabbit using the Synthetic peptide of Human DIO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using DIO2 Antibody(DIO2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: X200)
| Cat.No | ADC-26807A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DIO2 |
| Target Synonyms | DIO2; ITDI2; TXDI2; Type II iodothyronine deiodinase; 5DII; DIOII; Type 2 DI; Type-II 5'-deiodinase | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human DIO2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92813 |
Uniprot Id
Q92813
Target Species
Human
Target Name
DIO2
Target Full Name
Type II iodothyronine deiodinase
Target Function
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Target Subcellular Location
Membrane; Single-pass membrane protein.
Target Protein Families
Iodothyronine deiodinase family
Target Tissue Specificity
Isoform 1 is expressed in the lung, trachea, kidney, heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. Isoform 2 is expressed in the brain, heart, kidney and trachea.
Target Synonyms
DIO2; ITDI2; TXDI2; Type II iodothyronine deiodinase; 5DII; DIOII; Type 2 DI; Type-II 5'-deiodinase
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