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The antibody against DNASE2B was raised in rabbit using the Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against DNASE2B was raised in rabbit using the Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: A549 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate | All lanes: DNASE2B antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 42, 18 kDa | Observed band size: 42 kDa
| Cat.No | ADC-00688A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DNASE2B |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WZ79 |
Uniprot Id
Q8WZ79
Target Species
Human
Target Name
DNASE2B
Target Full Name
Deoxyribonuclease-2-beta
Target Function
Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Target Subcellular Location
Lysosome.
Target Protein Families
DNase II family
Target Tissue Specificity
Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.
Target Synonyms
DNASE2B; DLADDeoxyribonuclease-2-beta; EC 3.1.22.1; DNase II-like acid DNase; DNase2-like acid DNase; Deoxyribonuclease II beta; DNase II beta; Endonuclease DLAD
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