Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against DOCK10 was raised in rabbit using the Recombinant Human Dedicator of cytokinesis protein 10 protein (1645-2186AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against DOCK10 was raised in rabbit using the Recombinant Human Dedicator of cytokinesis protein 10 protein (1645-2186AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-25048A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DOCK10 |
| Target Synonyms | DOCK10 antibody; KIAA0694 antibody; ZIZ3Dedicator of cytokinesis protein 10 antibody; Zizimin-3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dedicator of cytokinesis protein 10 protein (1645-2186AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96BY6 |
Uniprot Id
Q96BY6
Target Species
Human
Target Name
DOCK10
Target Full Name
Dedicator of cytokinesis protein 10
Target Function
Guanine nucleotide-exchange factor (GEF) that activates CDC42 and RAC1 by exchanging bound GDP for free GTP. Essential for dendritic spine morphogenesis in Purkinje cells and in hippocampal neurons, via a CDC42-mediated pathway. Sustains B-cell lymphopoiesis in secondary lymphoid tissues and regulates FCER2/CD23 expression.
Target Subcellular Location
Nucleus. Cytoplasm. Cell projection, dendritic spine.
Target Protein Families
DOCK family
Target Tissue Specificity
Expressed at low level in brain and lung. Isoform 1 is enriched in normal T-cells, isoform 3 is enriched in normal B-cells and chronic lymphocytic leukemia (CLL) B-cells.
Target Synonyms
DOCK10; KIAA0694; ZIZ3Dedicator of cytokinesis protein 10; Zizimin-3
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
