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Rabbit anti-Human DPH3 Polyclonal Antibody

The antibody against DPH3 was raised in rabbit using the Recombinant Human DPH3 homolog protein (1-82AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-25046A

The antibody against DPH3 was raised in rabbit using the Recombinant Human DPH3 homolog protein (1-82AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-25046A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDPH3
Target SynonymsDPH3 antibody; DESR1 antibody; ZCSL2DPH3 homolog antibody; CSL-type zinc finger-containing protein 2 antibody; DelGEF-interacting protein 1 antibody; DelGIP1 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human DPH3 homolog protein (1-82AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ96FX2
Background Information
  • Uniprot Id

    Q96FX2

  • Target Species

    Human

  • Target Name

    DPH3

  • Target Full Name

    Diphthamide biosynthesis protein 3

  • Target Function

    Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).; Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    DPH3 family

  • Target Tissue Specificity

    Widely expressed with highest levels in small intestine, spleen, thymus, heart, liver and lung.

  • Target Synonyms

    DPH3; DESR1; ZCSL2DPH3 homolog; CSL-type zinc finger-containing protein 2; DelGEF-interacting protein 1; DelGIP1

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