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The antibody against DPT was raised in rabbit using the Recombinant Human Dermatopontin protein (19-201AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against DPT was raised in rabbit using the Recombinant Human Dermatopontin protein (19-201AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-16203A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DPT |
| Target Synonyms | DERM_HUMAN antibody; Dermatopontin antibody; Dpt antibody; TRAMP antibody; Tyrosine rich acidic matrix protein antibody; Tyrosine-rich acidic matrix protein antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dermatopontin protein (19-201AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q07507 |
Uniprot Id
Q07507
Target Species
Human
Target Name
DPT
Target Full Name
Dermatopontin
Target Function
Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation.
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Dermatopontin family
Target Tissue Specificity
Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fi
Target Synonyms
TRAMP; DPT
Target Background
Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin.
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