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The antibody against EID3 was raised in rabbit using the Synthetic peptide of Human EID3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against EID3 was raised in rabbit using the Synthetic peptide of Human EID3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-26791A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EID3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human EID3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N140 |
Uniprot Id
Q8N140
Target Species
Human
Target Name
EID3
Target Full Name
EP300-interacting inhibitor of differentiation 3
Target Function
Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.; Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors.
Target Subcellular Location
Nucleus. Cytoplasm. Chromosome, telomere.
Target Protein Families
NSE4 family
Target Tissue Specificity
Highly expressed in testis.
Target Synonyms
E1A-like inhibitor of differentiation 3; EID 3; EID-1-like inhibitor of differentiation 3; EID-3; EID3; EID3_HUMAN; EP300 interacting inhibitor of differentiation 3; EP300-interacting inhibitor of differentiation 3; FLJ25832; Non-SMC element 4; S. cerevisiae; homolog of; B; Non-structural maintenance of chromosomes element 4 homolog B; NSE4B; NSMCE4B
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