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The antibody against EIPR1 was raised in rabbit using the Recombinant Human EARP and GARP complex-interacting protein 1 protein (201-387AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against EIPR1 was raised in rabbit using the Recombinant Human EARP and GARP complex-interacting protein 1 protein (201-387AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human small intestine tissue using EIPR1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using EIPR1 Antibody at dilution of 1:1002
| Cat.No | ADC-23116A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EIPR1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human EARP and GARP complex-interacting protein 1 protein (201-387AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q53HC9 |
Uniprot Id
Q53HC9
Target Species
Human
Target Name
EIPR1
Target Full Name
EARP and GARP complex-interacting protein 1
Target Function
Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein(PubMed:27440922). Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex. Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles. Required for the stability of the endosome-associated retrograde protein (EARP) complex subunits and for proper localization and association of EARP with membranes.
Target Subcellular Location
Golgi apparatus, trans-Golgi network.
Target Protein Families
WD repeat EIPR1 family
Target Synonyms
EIPR1; TSSC1EARP and GARP complex-interacting protein 1; Endosome-associated recycling protein-interacting protein; Golgi-associated retrograde protein-interacting protein; Tumor-suppressing STF cDNA 1 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein
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