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The antibody against FLI1 was raised in rabbit using the Human FLI1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against FLI1 was raised in rabbit using the Human FLI1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48540A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FLI1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human FLI1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q01543 |
Uniprot Id
Q01543
Target Species
Human
Target Name
FLI1
Target Full Name
Friend leukemia integration 1 transcription factor
Target Function
Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.
Target Involvement
Ewing sarcoma (ES); Bleeding disorder, platelet-type 21 (BDPLT21)
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Research Area
Cancer
Target Synonyms
(Proto-oncogene Fli-1)(Transcription factor ERGB)
Target Background
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.
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