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The antibody against GMPR was raised in rabbit using the Recombinant Human GMP reductase 1 protein (1-345AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against GMPR was raised in rabbit using the Recombinant Human GMP reductase 1 protein (1-345AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver cancer using GMPR Antibody at dilution of 1:100
| Cat.No | ADC-49554A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GMPR |
| Target Synonyms | GMPR antibody; GMPR1GMP reductase 1 antibody; GMPR 1 antibody; EC 1.7.1.7 antibody; Guanosine 5'-monophosphate oxidoreductase 1 antibody; Guanosine monophosphate reductase 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human GMP reductase 1 protein (1-345AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P36959 |
Uniprot Id
P36959
Target Species
Human
Target Name
GMPR
Target Full Name
GMP reductase 1
Target Function
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
Target Protein Families
IMPDH/GMPR family, GuaC type 1 subfamily
Target Research Area
Cell Biology
Target Synonyms
GMPR; GMPR1GMP reductase 1; GMPR 1; EC 1.7.1.7; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1
Target Background
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.
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