Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against GMPS was raised in rabbit using the Human GMPS as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against GMPS was raised in rabbit using the Human GMPS as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48448A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GMPS |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human GMPS | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P49915 |
Uniprot Id
P49915
Target Species
Human
Target Name
GMPS
Target Full Name
GMP synthase [glutamine-hydrolyzing]
Target Function
Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.
Target Involvement
A chromosomal aberration involving GMPS is found in acute myeloid leukemias. Translocation t(3,11)(q25,q23) with KMT2A/MLL1.
Target Subcellular Location
Cytoplasm.
Target Synonyms
GATD7; Glutamine amidotransferase; GMP synthase [glutamine hydrolyzing]; GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Gmps; GUAA_HUMAN; Guanine monophosphate synthase; Guanine monphosphate synthetase; Guanosine 5' monophosphate synthase; MLL/GMPS fusion protein; Testicular tissue protein Li 82
Target Background
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
