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The antibody against GRM6 was raised in rabbit using the Synthesized peptide derived from Human GluR6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against GRM6 was raised in rabbit using the Synthesized peptide derived from Human GluR6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
$297.00
Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR6 antibody.
Western blot analysis of extracts from mouse brain, using GluR6 antibody.2
Western blot analysis of extracts from HepG2 cells (Lane 2), using mGluR6 antiobdy. The lane on the left is treated with synthesized peptide.3
| Cat.No | ADC-42400A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRM6 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human GluR6. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15303 |
Uniprot Id
O15303
Target Species
Human
Target Name
GRM6
Target Full Name
Metabotropic glutamate receptor 6
Target Function
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.
Target Involvement
Night blindness, congenital stationary, 1B (CSNB1B)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane.
Target Protein Families
G-protein coupled receptor 3 family
Target Tissue Specificity
Detected in melanocytes.
Target Synonyms
CSNB1B; DKFZp686H1993; GluR6; Glutamate receptor metabotropic 6; GPRC1F; Grm6; GRM6_HUMAN; Metabotropic glutamate receptor 6; mGlu6; mGluR6
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