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The antibody against GRM6 was raised in rabbit using the Recombinant Human Metabotropic glutamate receptor 6 protein (370-531AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against GRM6 was raised in rabbit using the Recombinant Human Metabotropic glutamate receptor 6 protein (370-531AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-02858A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRM6 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Metabotropic glutamate receptor 6 protein (370-531AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15303 |
Uniprot Id
O15303
Target Species
Human
Target Name
GRM6
Target Full Name
Metabotropic glutamate receptor 6
Target Function
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.
Target Involvement
Night blindness, congenital stationary, 1B (CSNB1B)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane.
Target Protein Families
G-protein coupled receptor 3 family
Target Tissue Specificity
Detected in melanocytes.
Target Synonyms
CSNB1B; DKFZp686H1993; GluR6; Glutamate receptor metabotropic 6; GPRC1F; Grm6; GRM6_HUMAN; Metabotropic glutamate receptor 6; mGlu6; mGluR6
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