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The antibody against H2AFB1 was raised in rabbit using the Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against H2AFB1 was raised in rabbit using the Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human liver tissue using H2AFB1 Antibody at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using H2AFB1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-22002A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | H2AFB1 |
| Target Synonyms | H2AB1 antibody; H2AFB1 antibody; Histone H2A-Bbd type 1 antibody; H2A Barr body-deficient antibody; H2A.B antibody; H2A.Bbd antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P0C5Y9 |
Uniprot Id
P0C5Y9
Target Species
Human
Target Name
H2AB1
Target Full Name
Histone H2A-Bbd type 1
Target Function
Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Histone H2A family
Target Tissue Specificity
Present in mature sperm.
Target Synonyms
H2AB1; H2AFB1; Histone H2A-Bbd type 1; H2A Barr body-deficient; H2A.B; H2A.Bbd
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