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The antibody against HAGH was raised in rabbit using the Recombinant Human Hydroxyacylglutathione hydrolase, mitochondrial protein (50-308AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against HAGH was raised in rabbit using the Recombinant Human Hydroxyacylglutathione hydrolase, mitochondrial protein (50-308AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using HAGH Antibody at dilution of 1:100
| Cat.No | ADC-54267A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HAGH |
| Target Synonyms | HAGH antibody; GLO2 antibody; HAGH1Hydroxyacylglutathione hydrolase antibody; mitochondrial antibody; EC 3.1.2.6 antibody; Glyoxalase II antibody; Glx II antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Hydroxyacylglutathione hydrolase, mitochondrial protein (50-308AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16775 |
Uniprot Id
Q16775
Target Species
Human
Target Name
HAGH
Target Full Name
Hydroxyacylglutathione hydrolase, mitochondrial
Target Function
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
Target Subcellular Location
[Isoform 1]: Mitochondrion matrix.; [Isoform 2]: Cytoplasm.
Target Protein Families
Metallo-beta-lactamase superfamily, Glyoxalase II family
Target Tissue Specificity
Expressed in liver and kidney.
Target Research Area
Metabolism
Target Synonyms
HAGH; GLO2; HAGH1Hydroxyacylglutathione hydrolase; mitochondrial; EC 3.1.2.6; Glyoxalase II; Glx II
Target Background
The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene.
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