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The antibody against HAO1 was raised in rabbit using the Recombinant Protein as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on WB, IHC.
The antibody against HAO1 was raised in rabbit using the Recombinant Protein as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on WB, IHC.
$167.00
Western blot analysis of 1) Mouse Liver Tissue, 2) Rat Liver Tissue using HAO1 Polyclonal Antibody.
| Cat.No | ADC-33095A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HAO1 |
| Form | Liquid | Species Reactivity | Mouse, Rat |
| Isotype | IgG | Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS |
| Conjugate | Non-conjugated | Application | IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UJM8 |
Uniprot Id
Q9UJM8
Target Species
Human
Target Name
HAO1
Target Full Name
2-Hydroxyacid oxidase 1
Target Function
Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
Target Subcellular Location
Peroxisome.
Target Protein Families
FMN-dependent alpha-hydroxy acid dehydrogenase family
Target Tissue Specificity
Liver.
Target Synonyms
(S) 2 hydroxy acid oxidase ; Glycolate oxidase; GOX; GOX1; HAO1; HAOX1; HAOX1_HUMAN; Hydroxyacid oxidase 1; MGC142225; MGC142227; OTTHUMP00000030231
Target Background
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
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