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The antibody against HECW2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NEDL2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against HECW2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NEDL2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of 3T3 cells using NEDL2 Polyclonal Antibody
| Cat.No | ADC-34385A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HECW2 |
| Target Synonyms | C2 and WW domain-containing protein 2 antibody; E3 ubiquitin protein ligase HECW2 antibody; E3 ubiquitin-protein ligase HECW2 antibody; HECT antibody; HECT | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human NEDL2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9P2P5 |
Uniprot Id
Q9P2P5
Target Species
Human
Target Name
HECW2
Target Full Name
E3 ubiquitin-protein ligase HECW2
Target Function
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition.
Target Involvement
Neurodevelopmental disorder with hypotonia, seizures, and absent language (NDHSAL)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, spindle.
Target Tissue Specificity
Predominantly expressed in adult brain, lung and heart.
Target Synonyms
C2 and WW domain-containing protein 2; E3 ubiquitin protein ligase HECW2; E3 ubiquitin-protein ligase HECW2; HECT; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2; Hecw2; HECW2_HUMAN; KIAA130; KIAA1301; NEDD4 like E3 ubiquitin protein ligase 2; NEDD4 Related E3 Ubiquitin Ligase; NEDD4-like E3 ubiquitin-protein ligase 2
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