Rabbit anti-Human Hemoglobin subunit alpha (HBA1) Polyclonal Antibody

The antibody against Hemoglobin subunit alpha (HBA1) was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human Hemoglobin subunit alpha (Hemoglobin subunit alpha (HBA1)) (NP_000549.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05574A

Number

Cat.No	ADA-05574A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	Hemoglobin subunit alpha (HBA1)
Target Synonyms	HBH; ECYT7; HBA-T3; METHBA; Hemoglobin subunit alpha (HBA1)	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	K-562	Application	ELISA, WB

Cat.No

ADA-05574A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

Hemoglobin subunit alpha (HBA1)

Target Synonyms

HBH; ECYT7; HBA-T3; METHBA; Hemoglobin subunit alpha (HBA1)

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

K-562

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Hemoglobin subunit alpha (Hemoglobin subunit alpha (HBA1)) (NP_000549.1).	Target Species	Human
Immunogen Sequence	MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFK	Uniprot ID	P69905

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Hemoglobin subunit alpha (Hemoglobin subunit alpha (HBA1)) (NP_000549.1).

Target Species

Human

Immunogen Sequence

MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFK

Uniprot ID

P69905

Background Information

Uniprot Id

P69905
Target Species

Human
Target Name

HBA1
Target Full Name

Hemoglobin subunit alpha
Target Function

Involved in oxygen transport from the lung to the various peripheral tissues.
Target Involvement

Heinz body anemias (HEIBAN); Alpha-thalassemia (A-THAL); Hemoglobin H disease (HBH)
Target Protein Families

Globin family
Target Tissue Specificity

Red blood cells.
Target Synonyms

HBH; ECYT7; HBA-T3; METHBA; Hemoglobin subunit alpha (HBA1)
Target Background

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Rabbit anti-Human Hemoglobin subunit alpha (HBA1) Polyclonal Antibody

Specifications

Immunogen Information

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