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The antibody against UL48 was raised in rabbit using the Recombinant Human herpesvirus 1 Tegument protein VP16 protein (1-490AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against UL48 was raised in rabbit using the Recombinant Human herpesvirus 1 Tegument protein VP16 protein (1-490AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-20542A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UL48 |
| Target Synonyms | UL48 antibody; Tegument protein VP16 antibody; Alpha trans-inducing protein antibody; Alpha-TIF antibody; ICP25 antibody; Vmw65 antibody | Form | Liquid |
| Species Reactivity | Human herpesvirus 1 | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human herpesvirus 1 Tegument protein VP16 protein (1-490AA) | Target Species | Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04486 |
Uniprot Id
P04486
Target Species
Human herpesvirus 1
Target Name
UL48
Target Function
Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection.; May play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis.
Target Subcellular Location
Virion tegument. Host nucleus.
Target Protein Families
Herpesviridae tegument protein VP16 protein family
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