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Rabbit anti-Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1) UL48 Polyclonal Antibody, Biotin conjugated

The antibody against UL48 was raised in rabbit using the Recombinant Human herpesvirus 1 Tegument protein VP16 protein (1-490AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-20542A

The antibody against UL48 was raised in rabbit using the Recombinant Human herpesvirus 1 Tegument protein VP16 protein (1-490AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-20542A ClonalityPolyclonal
Host SpeciesRabbitTarget NameUL48
Target SynonymsUL48 antibody; Tegument protein VP16 antibody; Alpha trans-inducing protein antibody; Alpha-TIF antibody; ICP25 antibody; Vmw65 antibodyFormLiquid
Species ReactivityHuman herpesvirus 1IsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateBiotin conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human herpesvirus 1 Tegument protein VP16 protein (1-490AA)Target SpeciesHuman herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP04486
Background Information
  • Uniprot Id

    P04486

  • Target Species

    Human herpesvirus 1

  • Target Name

    UL48

  • Target Function

    Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection.; May play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis.

  • Target Subcellular Location

    Virion tegument. Host nucleus.

  • Target Protein Families

    Herpesviridae tegument protein VP16 protein family

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