Rabbit anti-Human HEYL Polyclonal Antibody

The antibody against HEYL was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human HEYL (NP_055386.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06869A

Number

Cat.No	ADA-06869A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	HEYL
Target Synonyms	HEY3; HRT3; HESR3; bHLHb33; HEYL	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, MDA-MB-231, Molt-4(Negative control), U266	Application	ELISA, WB

Cat.No

ADA-06869A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

HEYL

Target Synonyms

HEY3; HRT3; HESR3; bHLHb33; HEYL

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, MDA-MB-231, Molt-4(Negative control), U266

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human HEYL (NP_055386.2).	Target Species	Human
Immunogen Sequence	MKRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHA	Uniprot ID	Q9NQ87

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human HEYL (NP_055386.2).

Target Species

Human

Immunogen Sequence

MKRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHA

Uniprot ID

Q9NQ87

Background Information

Uniprot Id

Q9NQ87
Target Species

Human
Target Name

HEYL
Target Full Name

Hairy/enhancer-of-split related with YRPW motif-like protein
Target Function

Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Target Subcellular Location

Nucleus.
Target Protein Families

HEY family
Target Synonyms

bHLHb33; Class B basic helix loop helix protein 33; Class B basic helix-loop-helix protein 33; Hairy enhancer of split related with YRPW motif like; Hairy related transcription factor 3; Hairy-related transcription factor 3; Hairy/enhancer of split related with YRPW motif 3; Hairy/enhancer of split related with YRPW motif like; Hairy/enhancer of split related with YRPW motif like protein; Hairy/enhancer-of-split related with YRPW motif-like protein; HEY like protein; HEY3; heyl; HEYL protein; HEYL_HUMAN; hHeyL; hHRT3; HRT 3; HRT-3; HRT3; MGC12623
Target Background

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Rabbit anti-Human HEYL Polyclonal Antibody

Specifications

Immunogen Information

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