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Rabbit anti-Human HHAT Polyclonal Antibody

The antibody against HHAT was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human HHAT (NP_060664.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05231A

The antibody against HHAT was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human HHAT (NP_060664.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-05231A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHHAT
Target SynonymsSkn; NNMS; SKI1; MART2; HHATFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesA375, K-562, Mouse brain, Rat spleenApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human HHAT (NP_060664.2).Target SpeciesHuman
Immunogen SequenceMLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWSFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYUniprot IDQ5VTY9
Background Information
  • Uniprot Id

    Q5VTY9

  • Target Species

    Human

  • Target Name

    HHAT

  • Target Full Name

    Protein-cysteine N-palmitoyltransferase HHAT

  • Target Function

    Palmitoyl acyltransferase that catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling. Promotes the transfer of palmitoyl-CoA from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane, where SHH palmitoylation occurs.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.

  • Target Protein Families

    Membrane-bound acyltransferase family, HHAT subfamily

  • Target Tissue Specificity

    Ubiquitously expressed in normal tissues and cancer cell lines.

  • Target Synonyms

    2810432O22Rik; AC115917.1; AI462858; FLJ10724; FLJ34867; Hedgehog acyltransferase; Hhat; HHAT_HUMAN; MART 2; MART-2; MART2; Melanoma antigen recognized by T cells 2; Melanoma antigen recognized by T-cells 2; MGC11697; OTTMUSP00000033669; Protein cysteine N palmitoyltransferase HHAT; Protein-cysteine N-palmitoyltransferase HHAT; RGD1311746; SKI1; Skinny hedgehog protein 1; Skinny hedgehog protein; Skn

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