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The antibody against HHEX was raised in rabbit using the Peptide sequence from Human Hematopoietically-expressed homeobox protein HHEX protein (187-204AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, Antigen affinity purified.
The antibody against HHEX was raised in rabbit using the Peptide sequence from Human Hematopoietically-expressed homeobox protein HHEX protein (187-204AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, Antigen affinity purified.
$299.00
| Cat.No | ADC-02217A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HHEX |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Antigen affinity purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence from Human Hematopoietically-expressed homeobox protein HHEX protein (187-204AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q03014 |
Uniprot Id
Q03014
Target Species
Human
Target Name
HHEX
Target Full Name
Hematopoietically-expressed homeobox protein HHEX
Target Function
Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. May play a role in hematopoietic differentiation.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Liver and promyelocytic leukemia cell line HL-60.
Target Synonyms
HEX; PRH; HMPH; PRHX; HOX11L-PEN; Hex
Target Background
This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.
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