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The antibody against HIST1H2BK was raised in rabbit using the Recombinant Human Histone H2B type 1-K protein (2-126AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against HIST1H2BK was raised in rabbit using the Recombinant Human Histone H2B type 1-K protein (2-126AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using HIST1H2BK Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using HIST1H2BK Antibody at dilution of 1:1002
| Cat.No | ADC-21997A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HIST1H2BK |
| Target Synonyms | H2BC12 antibody; H2BFT antibody; HIRIP1 antibody; HIST1H2BK antibody; Histone H2B type 1-K antibody; H2B K antibody; HIRA-interacting protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Histone H2B type 1-K protein (2-126AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60814 |
Uniprot Id
O60814
Target Species
Human
Target Name
H2BC12
Target Full Name
Histone H2B type 1-K
Target Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Histone H2B family
Target Research Area
Others
Target Synonyms
H2BC12; H2BFT; HIRIP1; HIST1H2BK; Histone H2B type 1-K; H2B K; HIRA-interacting protein 1
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