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The antibody against HNRNPLL was raised in rabbit using the Recombinant Human Heterogeneous nuclear ribonucleoprotein L-like protein (1-72AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against HNRNPLL was raised in rabbit using the Recombinant Human Heterogeneous nuclear ribonucleoprotein L-like protein (1-72AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-14737A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HNRNPLL |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Heterogeneous nuclear ribonucleoprotein L-like protein (1-72AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WVV9 |
Uniprot Id
Q8WVV9
Target Species
Human
Target Name
HNRNPLL
Target Full Name
Heterogeneous nuclear ribonucleoprotein L-like
Target Function
RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.
Target Tissue Specificity
Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.
Target Synonyms
BLOCK24; Heterogeneous nuclear ribonucleoprotein L like; Heterogeneous nuclear ribonucleoprotein L-like; HNRLL_HUMAN; hnRNPLL; HNRPLL; SRRF; Stromal RNA regulating factor ; Stromal RNA-regulating factor
Target Background
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).
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