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The antibody against HPD was raised in rabbit using the Recombinant Human 4-hydroxyphenylpyruvate dioxygenase protein (2-393AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against HPD was raised in rabbit using the Recombinant Human 4-hydroxyphenylpyruvate dioxygenase protein (2-393AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human colon cancer using HPD Antibody at dilution of 1:202
| Cat.No | ADC-46321A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HPD |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human 4-hydroxyphenylpyruvate dioxygenase protein (2-393AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P32754 |
Uniprot Id
P32754
Target Species
Human
Target Name
HPD
Target Full Name
4-hydroxyphenylpyruvate dioxygenase
Target Function
Key enzyme in the degradation of tyrosine.
Target Involvement
Tyrosinemia 3 (TYRSN3); Hawkinsinuria (HAWK)
Target Protein Families
4HPPD family
Target Research Area
Metabolism
Target Synonyms
4 HPPD; 4 hydroxyphenylpyruvate dioxygenase; 4 hydroxyphenylpyruvic acid oxidase; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; GLOD3 ; glyoxalase domain containing 3; HPD; HPPD_HUMAN; HPPDase; PPD
Target Background
The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
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