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The antibody against HPS5 was raised in rabbit using the Human HPS5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against HPS5 was raised in rabbit using the Human HPS5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-53096A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HPS5 |
| Target Synonyms | HPS5 antibody; AIBP63 antibody; KIAA1017 antibody; Hermansky-Pudlak syndrome 5 protein antibody; Alpha-integrin-binding protein 63 antibody; Ruby-eye protein 2 homolog antibody; Ru2 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human HPS5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UPZ3 |
Uniprot Id
Q9UPZ3
Target Species
Human
Target Name
HPS5
Target Full Name
BLOC-2 complex member HPS5
Target Function
May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins.
Target Involvement
Hermansky-Pudlak syndrome 5 (HPS5)
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
HPS5 family
Target Tissue Specificity
Widely expressed. Isoform 1:Highly expressed in lungs and testis. Isoform 2:Highly expressed in placenta, kidney, testis ovary, lung and thymus.
Target Synonyms
HPS5; AIBP63; KIAA1017; Hermansky-Pudlak syndrome 5 protein; Alpha-integrin-binding protein 63; Ruby-eye protein 2 homolog; Ru2
Target Background
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.
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