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The antibody against IARS2 was raised in rabbit using the Synthesized peptide derived from internal of Human IARS2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against IARS2 was raised in rabbit using the Synthesized peptide derived from internal of Human IARS2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
$297.00
Western blot analysis of extracts from RAW264.7 cells and COS-7 cells, using IARS2 antibody.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using IARS2 antibody.2
Immunofluorescence analysis of HepG2 cells, using IARS2 antibody.3
| Cat.No | ADC-41789A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IARS2 |
| Target Synonyms | 2010002H18Rik antibody; C79125 antibody; EC 6.1.1.5 antibody; FLJ10326 antibody; Iars2 antibody; IleRS antibody; isoleucine tRNA ligase 2, mitochondrial antibody; isoleucine tRNA ligase, mitochondrial antibody; isoleucine tRNA synthetase 2, mitochondrial antibody; Isoleucine--tRNA ligase antibody; isoleucine-tRNA synthetase 2 antibody; isoleucyl tRNA synthetase 2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human IARS2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NSE4 |
Uniprot Id
Q9NSE4
Target Species
Human
Target Name
IARS2
Target Full Name
Isoleucine--tRNA ligase, mitochondrial
Target Involvement
Cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia (CAGSSS)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Synonyms
2010002H18Rik; C79125; EC 6.1.1.5; FLJ10326; Iars2; IleRS; isoleucine tRNA ligase 2, mitochondrial; isoleucine tRNA ligase, mitochondrial; isoleucine tRNA synthetase 2, mitochondrial; Isoleucine--tRNA ligase; isoleucine-tRNA synthetase 2; isoleucyl tRNA synthetase 2, mitochondrial; Isoleucyl-tRNA synthetase; MGC63429; mitochondrial; mitochondrial isoleucine tRNA synthetase; rCG_20084; RGD1311857; SYIM_HUMAN
Target Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. This gene encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family.
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