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The antibody against ITPKA was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human IP3KA. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
The antibody against ITPKA was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human IP3KA. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
$167.00
Western Blot analysis of HuvEc cells using IP3KA Polyclonal Antibody
| Cat.No | ADC-38390A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ITPKA |
| Target Synonyms | 4, 5-trisphosphate 3-kinase A antibody; IP3 3-kinase A antibody; IP3K A antibody; InsP 3-kinase A antibody, ITPKA antibody; Inositol-trisphosphate 3-kinase A antibody; EC 2.7.1.127 antibody; Inositol 1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human IP3KA. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P23677 |
Uniprot Id
P23677
Target Species
Human
Target Name
ITPKA
Target Full Name
Inositol-trisphosphate 3-kinase A
Target Synonyms
ITPKA; Inositol-trisphosphate 3-kinase A; EC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A
Target Background
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins(1, 3, 4, 5)P4. The activity of the inositol 1, 4, 5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
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