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The antibody against KIF18A was raised in rabbit using the Human KIF18A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against KIF18A was raised in rabbit using the Human KIF18A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-48173A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KIF18A |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human KIF18A | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8NI77 |
Uniprot Id
Q8NI77
Target Species
Human
Target Name
KIF18A
Target Full Name
Kinesin-like protein KIF18A
Target Function
Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.
Target Subcellular Location
Cell projection, ruffle. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Target Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
Target Synonyms
AU024633; B130001M12Rik; DKFZp434G2226 ; KI18A_HUMAN; KIF 18A; KIF18A; kinesin family member 18A; Kinesin like protein KIF18A; Kinesin-like protein KIF18A; Marrow stromal KIF18A; MGC27627; MS KIF18A; MS-KIF18A; RGD1561740; RP23 206C1.1
Target Background
KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).
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