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The antibody against KLHL2 was raised in rabbit using the Recombinant Human Kelch-like protein 2 protein (1-155AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against KLHL2 was raised in rabbit using the Recombinant Human Kelch-like protein 2 protein (1-155AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human liver tissue using KLHL2 Antibody at dilution of 1:1002
| Cat.No | ADC-21959A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KLHL2 |
| Target Synonyms | ABP KELCH antibody; Actin binding protein Mayven antibody; Actin-binding protein Mayven antibody; kelch antibody; kelch like 2 antibody; Kelch like 2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Kelch-like protein 2 protein (1-155AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95198 |
Uniprot Id
O95198
Target Species
Human
Target Name
KLHL2
Target Full Name
Kelch-like protein 2
Target Function
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation. Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection. Cell projection, lamellipodium. Cytoplasm, cytosol.
Target Tissue Specificity
Ubiquitous. Detected throughout the brain.
Target Synonyms
ABP KELCH ; Actin binding protein Mayven ; Actin-binding protein Mayven; kelch; kelch like 2; Kelch like 2, Mayven; Kelch like family member 2; Kelch like protein 2; Kelch-like protein 2; KLHL2; KLHL2_HUMAN; MAV; MAYVEN ; OTTHUMP00000219997; OTTHUMP00000219998
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