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Rabbit anti-Human MRPL24 Polyclonal Antibody

The antibody against MRPL24 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MRP-L24. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-38198A

The antibody against MRPL24 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MRP-L24. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-38198A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPL24
Target SynonymsMRPL24 antibody; 39S ribosomal protein L24 antibody; mitochondrial antibody; L24mt antibody; MRP-L24 antibody; Mitochondrial large ribosomal subunit protein uL24m antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human MRP-L24.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ96A35
Background Information
  • Uniprot Id

    Q96A35

  • Target Species

    Human

  • Target Name

    MRPL24

  • Target Full Name

    Large ribosomal subunit protein uL24m

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Universal ribosomal protein uL24 family

  • Target Synonyms

    MRPL24; 39S ribosomal protein L24; mitochondrial; L24mt; MRP-L24; Mitochondrial large ribosomal subunit protein uL24m

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein.

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