Rabbit anti-Human MRPL28 Polyclonal Antibody

Uniprot Id

Q13084

Target Species

Human

Target Name

MRPL28

Target Full Name

Large ribosomal subunit protein bL28m

Target Subcellular Location

Mitochondrion.

Target Protein Families

Bacterial ribosomal protein bL28 family

Target Tissue Specificity

Found in a variety of normal tissues including spleen, testes, thymus, liver, kidney, brain, adrenal, lung and retinal tissue.

Target Research Area

Epigenetics and Nuclear Signaling

Target Synonyms

39S ribosomal protein L28; 39S ribosomal protein L28 mitochondrial; 39S ribosomal protein L28 mitochondrial precursor ; HGNC6756 ; L28mt; MAAT 1; MAAT1; Melanoma antigen p15; Melanoma associated antigen recognised by cytotoxic T lymphocytes; Melanoma associated antigen recognized by T lymphocytes; Melanoma-associated antigen recognized by T-lymphocytes; MGC8499; mitochondrial; Mitochondrial ribosomal protein L28; MRP L28; MRP-L28; MRPL 28; mrpl28; P15 ; RM28_HUMAN

Target Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion.