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The antibody against MRPL33 was raised in rabbit using the Recombinant Human 39S ribosomal protein L33, mitochondrial protein (1-65AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against MRPL33 was raised in rabbit using the Recombinant Human 39S ribosomal protein L33, mitochondrial protein (1-65AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human heart tissue using MRPL33 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using MRPL33 Antibody at dilution of 1:1002
| Cat.No | ADC-24390A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL33 |
| Target Synonyms | 39S ribosomal protein L33 antibody; L33mt antibody; mitochondrial antibody; MRP-L33 antibody; mRpL33 antibody; RM33_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human 39S ribosomal protein L33, mitochondrial protein (1-65AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75394 |
Uniprot Id
O75394
Target Species
Human
Target Name
MRPL33
Target Full Name
Large ribosomal subunit protein bL33m
Target Subcellular Location
Mitochondrion.
Target Protein Families
Bacterial ribosomal protein bL33 family
Target Synonyms
39S ribosomal protein L33; L33mt; mitochondrial; MRP-L33; mRpL33; RM33_HUMAN
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternatively spliced transcript variants encoding different isoforms have been described.
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