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The antibody against MYBPC2 was raised in rabbit using the Recombinant Human Myosin-binding protein C, fast-type protein (739-1141AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against MYBPC2 was raised in rabbit using the Recombinant Human Myosin-binding protein C, fast-type protein (739-1141AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MYBPC2 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using MYBPC2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-10451A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MYBPC2 |
| Target Synonyms | C protein, fast type antibody; Myosin-binding protein C, fast-type antibody; MYPC2_HUMAN antibody; skeletal muscle fast isoform antibody, skeletal muscle fast isoform antibody; C-protein antibody; Fast MyBP C antibody; Fast MyBP-C antibody; MGC163408 antibody; MYBPC antibody; Mybpc2 antibody; MYBPCF antibody; Myosin binding protein C | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Myosin-binding protein C, fast-type protein (739-1141AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14324 |
Uniprot Id
Q14324
Target Species
Human
Target Name
MYBPC2
Target Full Name
Myosin-binding protein C, fast-type
Target Function
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Target Protein Families
Immunoglobulin superfamily, MyBP family
Target Research Area
Signal Transduction
Target Synonyms
C protein, skeletal muscle fast isoform; C-protein; Fast MyBP C; Fast MyBP-C; MGC163408; MYBPC; Mybpc2; MYBPCF; Myosin binding protein C, fast type; Myosin-binding protein C, fast-type; MYPC2_HUMAN; skeletal muscle fast isoform
Target Background
This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively.
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