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The antibody against MYOM2 was raised in rabbit using the Synthesized peptide derived from internal of Human MYOM2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against MYOM2 was raised in rabbit using the Synthesized peptide derived from internal of Human MYOM2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from COS-7 cells and HT-29 cells, using MYOM2 antibody.
| Cat.No | ADC-41116A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MYOM2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human MYOM2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P54296 |
Uniprot Id
P54296
Target Species
Human
Target Name
MYOM2
Target Full Name
Myomesin-2
Target Function
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
Target Subcellular Location
Cytoplasm, myofibril, sarcomere, M line.
Target Synonyms
165 kDa connectin associated protein; 165 kDa connectin-associated protein; 165 kDa titin associated protein; 165 kDa titin-associated protein; M band protein; M protein; M-protein; MYOM 2; MYOM2; MYOM2_HUMAN; Myomesin (M protein) 2 (165kD); Myomesin (M protein) 2 165kDa; Myomesin (M protein) 2; Myomesin 2; Myomesin family member 2; Myomesin-2; Titin associated protein 165 kD; Titin associated protein; TTNAP
Target Background
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1, 465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical.
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