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Rabbit anti-Human NFATC2IP Polyclonal Antibody

The antibody against NFATC2IP was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NFATc2IP. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-33539A

The antibody against NFATC2IP was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NFATc2IP. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-33539A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNFATC2IP
Target Synonyms45 kDa NF-AT-interacting protein antibody; 45 kDa NFAT-interacting protein antibody; cytoplasmic 2-interacting protein antibody; ESC2 antibody; NF2IP_HUMAN antibody; NFAT-interacting protein, 45-KD antibody; NFATC2-interacting protein antibody; Nfatc2ip antibody; NIP45 antibody; Nuclear factor of activated T-cells antibody; Nuclear factor of activated T-cells, calcineurin-dependent 2 interacting protein antibody; RAD60 antibody, cytoplasmic, cytoplasmic 2-interacting protein antibody; nuclear factor of activated T-cellsFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human NFATc2IP.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8NCF5
Background Information
  • Uniprot Id

    Q8NCF5

  • Target Species

    Human

  • Target Name

    NFATC2IP

  • Target Full Name

    NFATC2-interacting protein

  • Target Function

    In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.

  • Target Subcellular Location

    Nucleus. Cytoplasm.

  • Target Synonyms

    45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; cytoplasmic 2-interacting protein; ESC2; NF2IP_HUMAN; NFAT-interacting protein, 45-KD; NFATC2-interacting protein; Nfatc2ip; NIP45; Nuclear factor of activated T-cells; Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein; RAD60

  • Target Background

    Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus.

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