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The antibody against NFE2L3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 330-550 of human NFE2L3 (NP_004280.5) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against NFE2L3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 330-550 of human NFE2L3 (NP_004280.5) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-04855A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NFE2L3 |
| Target Synonyms | NRF3; NFE2L3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, RAW264.7 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 330-550 of human NFE2L3 (NP_004280.5). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y4A8 | Immunogen Sequence |
Uniprot Id
Q9Y4A8
Target Species
Human
Target Name
NFE2L3
Target Full Name
Nuclear factor erythroid 2-related factor 3
Target Function
Activates erythroid-specific, globin gene expression.
Target Subcellular Location
Nucleus.
Target Protein Families
BZIP family, CNC subfamily
Target Tissue Specificity
Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas.
Target Synonyms
NFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2; like 3
Target Background
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
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