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The antibody against NFE2L3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Nrf3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against NFE2L3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Nrf3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of HeLa cells using Nrf3 Polyclonal Antibody
Western Blot analysis of K562 NIH-3T3 cells using Nrf3 Polyclonal Antibody2
| Cat.No | ADC-38054A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NFE2L3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Nrf3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y4A8 |
Uniprot Id
Q9Y4A8
Target Species
Human
Target Name
NFE2L3
Target Full Name
Nuclear factor erythroid 2-related factor 3
Target Function
Activates erythroid-specific, globin gene expression.
Target Subcellular Location
Nucleus.
Target Protein Families
BZIP family, CNC subfamily
Target Tissue Specificity
Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas.
Target Synonyms
NFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2; like 3
Target Background
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
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