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The antibody against NLRC5 was raised in rabbit using the Recombinant Human Protein NLRC5 protein (95-208AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against NLRC5 was raised in rabbit using the Recombinant Human Protein NLRC5 protein (95-208AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-05652A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NLRC5 |
| Target Synonyms | CARD domain containing 5 antibody; NLR family, CARD-containing 5 antibody; NLR family, Caterpiller protein 16.1 antibody; CLR16.1 antibody; FLJ21709 antibody; FLJ39711 antibody; NLR family | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein NLRC5 protein (95-208AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86WI3 |
Uniprot Id
Q86WI3
Target Species
Human
Target Name
NLRC5
Target Full Name
Protein NLRC5
Target Function
Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.
Target Subcellular Location
Cytoplasm.
Target Protein Families
NLRP family
Target Tissue Specificity
Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate.
Target Synonyms
Caterpiller protein 16.1; CLR16.1; FLJ21709; FLJ39711; NLR family, CARD domain containing 5; NLR family, CARD-containing 5; NLR family, caspase recruitment domain-containing 5; NLRC5; NLRC5_HUMAN; NOD-like receptor C5; NOD27; NOD4; Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5 ; nucleotide-binding oligomerization domains 27; OTTHUMP00000164675; Protein Caterpiller 16.1; Protein NLRC5
Target Background
This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.
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