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Rabbit anti-Human NPM3 Polyclonal Antibody

The antibody against NPM3 was raised in rabbit using the Human NPM3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-47783A

The antibody against NPM3 was raised in rabbit using the Human NPM3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-47783A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNPM3
Target Synonyms3 antibody; Nucleoplasmin 3 antibody; Nucleoplasmin-3 antibody; PORMIN antibody; RGD1565542 antibody; TMEM123 antibody, member 3 antibody; nucleophosmin/nucleoplasmin, NPM 3 antibody; NPM3 antibody; NPM3_HUMAN antibody; Nub1 antibody; nucleophosmin/nucleoplasmin familyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NPM3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO75607
Background Information
  • Uniprot Id

    O75607

  • Target Species

    Human

  • Target Name

    NPM3

  • Target Full Name

    Nucleoplasmin-3

  • Target Function

    Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning. Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM. Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM.

  • Target Subcellular Location

    Nucleus. Nucleus, nucleolus.

  • Target Protein Families

    Nucleoplasmin family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    NPM 3; NPM3; NPM3_HUMAN; Nub1; nucleophosmin/nucleoplasmin family, member 3; nucleophosmin/nucleoplasmin, 3; Nucleoplasmin 3; Nucleoplasmin-3; PORMIN; RGD1565542; TMEM123

  • Target Background

    The protein encoded by this gene is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. This protein is strongly expressed in diverse cell types where it localizes primarily to the nucleus. Based on its similarity to nucleoplasmin and nucleophosmin, this protein likely functions as a molecular chaperone in the cell nucleus.

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