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Rabbit anti-Human NRDC Polyclonal Antibody

The antibody against NRDC was raised in rabbit using the Recombinant Human Nardilysin protein (32-113AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

ADC-06828A

The antibody against NRDC was raised in rabbit using the Recombinant Human Nardilysin protein (32-113AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

$299.00

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Specifications


Cat.No ADC-06828A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNRDC
Target SynonymsNRDC antibody; NRD1 antibody; Nardilysin antibody; EC 3.4.24.61 antibody; N-arginine dibasic convertase antibody; NRD convertase antibody; NRD-C antibody; Nardilysin convertase antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Nardilysin protein (32-113AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO43847
Background Information
  • Uniprot Id

    O43847

  • Target Species

    Human

  • Target Name

    NRDC

  • Target Full Name

    Nardilysin

  • Target Function

    Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.

  • Target Protein Families

    Peptidase M16 family

  • Target Tissue Specificity

    Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues.

  • Target Synonyms

    NRDC; NRD1; Nardilysin; EC 3.4.24.61; N-arginine dibasic convertase; NRD convertase; NRD-C; Nardilysin convertase

  • Target Background

    This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.

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