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Rabbit anti-Human OGN Polyclonal Antibody

The antibody against OGN was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Osteoglycin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-37059A

The antibody against OGN was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Osteoglycin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-37059A ClonalityPolyclonal
Host SpeciesRabbitTarget NameOGN
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the C-terminal region of Human Osteoglycin.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP20774
Background Information
  • Uniprot Id

    P20774

  • Target Species

    Human

  • Target Name

    OGN

  • Target Full Name

    Mimecan

  • Target Function

    Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix.

  • Target Protein Families

    Small leucine-rich proteoglycan (SLRP) family, SLRP class III subfamily

  • Target Tissue Specificity

    Bone.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    Corneal keratan sulfate proteoglycan; DKFZP586P2421; MIME_HUMAN; Mimecan; Mimecan proteoglycan; OG; OGN; OIF; Osteoglycin; Osteoinductive factor; SLRR3A

  • Target Background

    This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants.

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