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The antibody against PAX2 was raised in rabbit using the Synthetic peptide of Human PAX2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against PAX2 was raised in rabbit using the Synthetic peptide of Human PAX2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-28040A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PAX2 |
| Target Synonyms | PAX2 antibody; Paired box protein Pax-2 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human PAX2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q02962 |
Uniprot Id
Q02962
Target Species
Human
Target Name
PAX2
Target Full Name
Paired box protein Pax-2
Target Function
Transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
Target Involvement
Papillorenal syndrome (PAPRS); Focal segmental glomerulosclerosis 7 (FSGS7)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.
Target Research Area
Developmental Biology
Target Synonyms
PAX2; Paired box protein Pax-2
Target Background
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
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