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Rabbit anti-Human PDCL3 Polyclonal Antibody

The antibody against PDCL3 was raised in rabbit using the Recombinant Human Phosducin-like protein 3 protein (1-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

ADC-00773A

The antibody against PDCL3 was raised in rabbit using the Recombinant Human Phosducin-like protein 3 protein (1-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

$299.00

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Specifications


Cat.No ADC-00773A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePDCL3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Phosducin-like protein 3 protein (1-239AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9H2J4
Background Information
  • Uniprot Id

    Q9H2J4

  • Target Species

    Human

  • Target Name

    PDCL3

  • Target Full Name

    Phosducin-like protein 3

  • Target Function

    Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation. Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding. Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes. Modulates the activation of caspases during apoptosis.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum.

  • Target Protein Families

    Phosducin family

  • Target Tissue Specificity

    Expressed in endothelial cells (at protein level). Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine and colon.

  • Target Synonyms

    HTPHLP; IAP associated factor VIAF1; MGC3062; PDCL 3; Pdcl3; PDCL3_HUMAN; PHLP2A; PHLP3; Phosducin like 3; Phosducin like protein 3; Phosducin-like protein 3; PhPL3; VIAF 1; VIAF; VIAF-1; VIAF1; Viral IAP associated factor 1; Viral IAP-associated factor 1

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