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The antibody against PDGFRL was raised in rabbit using the Recombinant Human Platelet-derived growth factor receptor-like protein (15-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against PDGFRL was raised in rabbit using the Recombinant Human Platelet-derived growth factor receptor-like protein (15-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-16765A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDGFRL |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Platelet-derived growth factor receptor-like protein (15-205AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15198 |
Uniprot Id
Q15198
Target Species
Human
Target Name
PDGFRL
Target Full Name
Platelet-derived growth factor receptor-like protein
Target Involvement
Colorectal cancer (CRC)
Target Subcellular Location
Secreted.
Target Tissue Specificity
Expressed in colon, lung and liver.
Target Synonyms
PDGF receptor beta like tumor suppressor ; PDGF receptor beta-like tumor suppressor; PDGFR-like protein; Pdgfrl; PDGRL; PGFRL_HUMAN; Platelet-derived growth factor receptor-like protein; PRLTS
Target Background
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
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