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Rabbit anti-Human PDGFRL Polyclonal Antibody

The antibody against PDGFRL was raised in rabbit using the Recombinant Human Platelet-derived growth factor receptor-like protein (15-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-16765A

The antibody against PDGFRL was raised in rabbit using the Recombinant Human Platelet-derived growth factor receptor-like protein (15-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-16765A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePDGFRL
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Platelet-derived growth factor receptor-like protein (15-205AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ15198
Background Information
  • Uniprot Id

    Q15198

  • Target Species

    Human

  • Target Name

    PDGFRL

  • Target Full Name

    Platelet-derived growth factor receptor-like protein

  • Target Involvement

    Colorectal cancer (CRC)

  • Target Subcellular Location

    Secreted.

  • Target Tissue Specificity

    Expressed in colon, lung and liver.

  • Target Synonyms

    PDGF receptor beta like tumor suppressor ; PDGF receptor beta-like tumor suppressor; PDGFR-like protein; Pdgfrl; PDGRL; PGFRL_HUMAN; Platelet-derived growth factor receptor-like protein; PRLTS

  • Target Background

    This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.

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