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The antibody against PGK2 was raised in rabbit using the Fusion protein of Human PGK2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PGK2 was raised in rabbit using the Fusion protein of Human PGK2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-30720A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PGK2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human PGK2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P07205 |
Uniprot Id
P07205
Target Species
Human
Target Name
PGK2
Target Full Name
Phosphoglycerate kinase 2
Target Function
Essential for sperm motility and male fertility. Not required for the completion of spermatogenesis.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Phosphoglycerate kinase family
Target Tissue Specificity
Mainly found in round spermatids. Localized on the principle piece in the sperm (at protein level). Testis-specific. Expression significantly decreased in the testis of elderly men.
Target Synonyms
dJ417L20.2; PGK 2; pgk2; PGK2_HUMAN; PGKB; PGKPS; Phosphoglycerate kinase 2; Phosphoglycerate kinase; Phosphoglycerate kinase autosomal pseudogene; Phosphoglycerate kinase testis specific; testis specific
Target Background
This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1, 3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.
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