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Rabbit anti-Human Phospho-TENC1 (Y483) Polyclonal Antibody

The antibody against TNS2 was raised in rabbit using the Synthesized peptide derived from Human Tensin-2 around the phosphorylation site of Y483. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-35807A

The antibody against TNS2 was raised in rabbit using the Synthesized peptide derived from Human Tensin-2 around the phosphorylation site of Y483. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-35807A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTNS2
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Human Tensin-2 around the phosphorylation site of Y483.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ63HR2
Background Information
  • Uniprot Id

    Q63HR2

  • Target Species

    Human

  • Target Name

    TNS2

  • Target Full Name

    Tensin-2

  • Target Function

    Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin. In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy. Negatively regulates PI3K-AKT pathway activation.

  • Target Subcellular Location

    Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Tissue Specificity

    Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine.

  • Target Synonyms

    C1 domain containing phosphatase and tensin homolog; C1 domain-containing phosphatase and tensin homolog; C1 TEN; C1-TEN; C1TEN; DKFZp686D13244; FLJ16320; KIAA1075; TENC 1; TENC1; TENC1_HUMAN; Tensin 2; Tensin like C1 domain containing phosphatase; Tensin-2; Tensin-like C1 domain-containing phosphatase; TNS2

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