Rabbit anti-Human POLL Polyclonal Antibody

The antibody against POLL was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 421-575 of human POLL (NP_037406.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01391A

Number

Cat.No	ADA-01391A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	POLL
Target Synonyms	BETAN; POLKAPPA; POLL	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-549, HL-60, MCF7, NCI-H460, Rat liver	Application	ELISA, WB

Cat.No

ADA-01391A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

POLL

Target Synonyms

BETAN; POLKAPPA; POLL

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-549, HL-60, MCF7, NCI-H460, Rat liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 421-575 of human POLL (NP_037406.1).	Target Species	Human
Immunogen Sequence	GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW	Uniprot ID	Q9UGP5

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 421-575 of human POLL (NP_037406.1).

Target Species

Human

Immunogen Sequence

GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW

Uniprot ID

Q9UGP5

Background Information

Uniprot Id

Q9UGP5
Target Species

Human
Target Name

POLL
Target Full Name

DNA polymerase lambda
Target Function

DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Target Subcellular Location

Nucleus. Chromosome.
Target Protein Families

DNA polymerase type-X family
Target Tissue Specificity

Expressed in a number of tissues. Abundant in testis.
Target Synonyms

BETA N; BETAN; DNA directed DNA polymerase lambda; DNA polymerase beta 2; DNA polymerase beta-2; DNA polymerase kappa; DNA polymerase kappa DNA polymerase beta N; DNA polymerase lambda; DNA polymerase lamda2; DPOLL_HUMAN; EC 2.7.7.7,EC 4.2.99.; FLJ46002; OTTHUMP00000020321; OTTHUMP00000020323; OTTHUMP00000059179; Pol beta2; POL KAPPA; Pol Lambda; POLKAPPA; POLL; Polymerase DNA directed lambda
Target Background

This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described.

Rabbit anti-Human POLL Polyclonal Antibody

Specifications

Immunogen Information

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