Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against PPP4R2 was raised in rabbit using the Synthesized peptide derived from internal of Human PP4R2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against PPP4R2 was raised in rabbit using the Synthesized peptide derived from internal of Human PP4R2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from K562 cells and COS-7 cells, using PP4R2 antibody.
| Cat.No | ADC-40919A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPP4R2 |
| Target Synonyms | BE691708 antibody; C230060M08Rik antibody; MGC131930 antibody; PP4R2 antibody; PP4R2_HUMAN antibody; PPP4R2 antibody; protein phosphatase 4, regulatory subunit 2 antibody; Serine/threonine protein phosphatase 4 regulatory subunit 2 antibody; Serine/threonine-protein phosphatase 4 regulatory subunit 2 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human PP4R2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NY27 |
Uniprot Id
Q9NY27
Target Species
Human
Target Name
PPP4R2
Target Full Name
Serine/threonine-protein phosphatase 4 regulatory subunit 2
Target Function
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair.
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=Ionizing radiation induces relocalization to nuclear foci and colocalization with RPA2.
Target Protein Families
PPP4R2 family
Target Tissue Specificity
Widely expressed.
Target Synonyms
BE691708; C230060M08Rik; MGC131930 ; PP4R2; PP4R2_HUMAN; PPP4R2; protein phosphatase 4, regulatory subunit 2; Serine/threonine protein phosphatase 4 regulatory subunit 2; Serine/threonine-protein phosphatase 4 regulatory subunit 2
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
