Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against PRDM16 was raised in rabbit using the Recombinant Human PR domain zinc finger protein 16 protein (448-683AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against PRDM16 was raised in rabbit using the Recombinant Human PR domain zinc finger protein 16 protein (448-683AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human brain tissue using PRDM16 Antibody at dilution of 1:100
Immunofluorescent analysis of PC-3 cells using PRDM16 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-10101A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRDM16 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human PR domain zinc finger protein 16 protein (448-683AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HAZ2 |
Uniprot Id
Q9HAZ2
Target Species
Human
Target Name
PRDM16
Target Full Name
Histone-lysine N-methyltransferase PRDM16
Target Function
Binds DNA and functions as a transcriptional regulator. Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro. Probably catalyzes the monomethylation of free histone H3 in the cytoplasm which is then transported to the nucleus and incorporated into nucleosomes where SUV39H methyltransferases use it as a substrate to catalyze histone H3 'Lys-9' trimethylation. Likely to be one of the primary histone methyltransferases along with MECOM/PRDM3 that direct cytoplasmic H3K9me1 methylation. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions as a repressor of TGF-beta signaling.; Binds DNA and functions as a transcriptional regulator. Functions as a repressor of TGF-beta signaling. May regulate granulocyte differentiation.
Target Involvement
Left ventricular non-compaction 8 (LVNC8); Cardiomyopathy, dilated 1LL (CMD1LL)
Target Subcellular Location
Nucleus. Cytoplasm.
Target Tissue Specificity
Expressed in uterus and kidney. Expressed in both cardiomyocytes and interstitial cells.
Target Synonyms
CMD1LL; KIAA1675; LVNC8; MDS1/EVI1 like gene 1; MDS1/EVI1-like gene 1; MEL1; PFM 13; PFM13; PR domain containing 16; PR domain containing protein 16; PR domain zinc finger protein 16; PR domain-containing protein 16; PRD16_HUMAN; Prdm16; Transcription factor MEL 1; Transcription factor MEL1
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
