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Rabbit anti-Human PRPF4 Polyclonal Antibody

The antibody against PRPF4 was raised in rabbit using the Human PRPF4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-52227A

The antibody against PRPF4 was raised in rabbit using the Human PRPF4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-52227A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePRPF4
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman PRPF4Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO43172
Background Information
  • Uniprot Id

    O43172

  • Target Species

    Human

  • Target Name

    PRPF4

  • Target Full Name

    U4/U6 small nuclear ribonucleoprotein Prp4

  • Target Function

    Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

  • Target Involvement

    Retinitis pigmentosa 70 (RP70)

  • Target Subcellular Location

    Nucleus. Nucleus speckle.

  • Target Synonyms

    hPrp4; HPRP4P ; PRP4 ; PRP4 homolog; PRP4 pre mRNA processing factor 4 homolog (yeast); PRP4/STK/WD splicing factor; PRP4_HUMAN; Prp4p ; PRPF4; RP70; SNRNP60; U4/U6 small nuclear ribonucleoprotein Prp4; U4/U6 snRNP 60 kDa protein; WD splicing factor Prp4

  • Target Background

    The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene.

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