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The antibody against PRPF4 was raised in rabbit using the Human PRPF4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PRPF4 was raised in rabbit using the Human PRPF4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-52227A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRPF4 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human PRPF4 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43172 |
Uniprot Id
O43172
Target Species
Human
Target Name
PRPF4
Target Full Name
U4/U6 small nuclear ribonucleoprotein Prp4
Target Function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
Target Involvement
Retinitis pigmentosa 70 (RP70)
Target Subcellular Location
Nucleus. Nucleus speckle.
Target Synonyms
hPrp4; HPRP4P ; PRP4 ; PRP4 homolog; PRP4 pre mRNA processing factor 4 homolog (yeast); PRP4/STK/WD splicing factor; PRP4_HUMAN; Prp4p ; PRPF4; RP70; SNRNP60; U4/U6 small nuclear ribonucleoprotein Prp4; U4/U6 snRNP 60 kDa protein; WD splicing factor Prp4
Target Background
The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene.
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